Bradl came into the sport in 2005 where he took part in three races of the 125cc series.

He won the Moto2 class in 2011 after his title rival Marc Márquez missed the final two races due to injury and this put Bradl into the top class for 2012.

He scored his first MotoGP pole position at the 2013 U.S. Grand Prix at Laguna Seca.